Glycaemic, blood pressure and lowdensity lipoprotein-cholesterol control among patients with diabetes mellitus in a specialised clinic in Botswana: a cross-sectional study

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dc.contributor.authorMwita, Julius Chacha
dc.contributor.authorFrancis, Joel M
dc.contributor.authorOmech, Bernard
dc.contributor.authorBotsile, Elizabeth
dc.contributor.authorOyewo, Aderonke
dc.contributor.authorMokgwathi, Matshidiso
dc.contributor.authorMolefe-Baikai, Onkabetse Julia
dc.contributor.authorGodman, Brian
dc.contributor.authorTshikuka, Jose-Gaby
dc.date.accessioned2021-11-22T11:55:55Z
dc.date.available2021-11-22T11:55:55Z
dc.date.issued2019
dc.description.abstractObjective Control of glycaemic, hypertension and lowdensity lipoprotein-cholesterol (LDL-C) among patients with type 2 diabetes mellitus (T2DM) is vital for the prevention of cardiovascular diseases. The current study was an audit of glycaemic, hypertension and LDL-C control among ambulant patients with T2DM in Botswana. Also, the study aimed at assessing factors associated with attaining optimal glycaemic, hypertension and LDL-C therapeutic goals. Design A cross-sectional study. Setting A specialised public diabetes clinic in Gaborone, Botswana. Participants Patients with T2DM who had attended the clinic for ≥3 months between August 2017 and February 2018. Primary outcome measure The proportion of patients with optimal glycaemic (HbA1c<7%), hypertension (blood pressure <140/90 mm Hg) and LDL-C (<1.8 mmol/L) control. Results The proportions of patients meeting optimal targets were 32.3% for glycaemic, 54.2% for hypertension and 20.4% for LDL-C. Age≥ 50 years was positively associated with optimal glycaemic control (adjusted OR [AOR] 5.79; 95% CI 1.08 to 31.14). On the other hand, an increase in diabetes duration was inversely associated with optimal glycemic control (AOR 0.91; 95% CI 0.85 to 0.98). Being on an ACE inhibitor was inversely associated with optimal hypertension control (AOR 0.35; 95% CI 0.14 to 0.85). Being female was inversely associated with optimal LDL-C control (AOR 0.24; 95% CI (0.09 - 0.59). Conclusion Patients with T2DM in Gaborone, Botswana, presented with suboptimal control of recommended glycaemic, hypertension and LDL-C targets. These findings call for urgent individual and health systems interventions to address key determinants of the recommended therapeutic targets among patients with diabetes in this setting.en_US
dc.identifier.citationMwita JC, Francis JM, Omech B, et al. Glycaemic, blood pressure and low-density lipoprotein-cholesterol control among patients with diabetes mellitus in a specialised clinic in Botswana: a crosssectional study. BMJ Open 2019;9:e026807. doi:10.1136/ bmjopen-2018-026807en_US
dc.identifier.uridoi:10.1136/ bmjopen-2018-026807
dc.identifier.urihttps://hdl.handle.net/123456789/347
dc.publisherBMJ Openen_US
dc.subjectGlycaemic blood pressure diabetes mellitus low density lipoprotein-cholesterolen_US
dc.titleGlycaemic, blood pressure and lowdensity lipoprotein-cholesterol control among patients with diabetes mellitus in a specialised clinic in Botswana: a cross-sectional studyen_US
dc.typeArticleen_US

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